“Exact 2-kDa hyaluronan evidence: topical 0.1% HA2k improved facial wrinkles and increased dermal collagen density, linked to collagen remodeling.”
Hyaluronic Acid (Nano Molecule, 2000daltons)
Cosmetics
Code: 35934
Nano 2,000-3,000 Da Hydrolyzed Hyaluronic Acid powder for light anti-aging hydration formulas with minimal gel build.
Hyaluronic Acid (Nano Molecule, 2000daltons) is a cosmetic hyaluronic acid powder for water-based moisturising formulas.
This grade is Hydrolyzed Hyaluronic Acid with molecular weight 2,000-3,000 Da. It is designed for low molecular weight hydration with a light, non-gel feel.
Molecular weight strongly changes how hyaluronic acid behaves in a formula: lower molecular weight grades give a lighter skin feel, while higher molecular weight grades contribute more surface hydration, viscosity and film feel.
Product Description: This nano-grade hydrolyzed hyaluronic acid gives a very light skin feel with minimal viscosity build. It is useful in anti-aging hydration serums, essences, toners and low-body emulsions where a formulator wants hyaluronic acid benefits without a heavy surface film.
COA specification includes sodium hyaluronate minimum 95%, glucuronic acid minimum 46%, molecular weight 2,000-3,000 Da and pH 5.0-8.5 in 0.5% water solution.
When the formula is not already preserved, add an appropriate preservative system. Hydrated hyaluronic acid gels are water-rich systems and can lose viscosity or become contaminated without preservation.
Usage: Suitable for hydrating serums, gels, lotions, creams, masks, essences and other water-phase cosmetic products.
Mixing method:
- Disperse slowly into the water phase while mixing. Sprinkle onto the water surface gradually to avoid clumps.
- For small lab batches without a homogenizer, shake or mix well, then allow time for full hydration before final viscosity adjustment.
- Maintain final formula pH about 3-9 and avoid unnecessary high heat or excessive shear after hydration.
Usage rate: 0.1-0.5%
Product characteristics: White powder, molecular weight 2,000-3,000 Da.
Solubility: Water soluble. Hydration is easier when the powder is added slowly into a moving water phase.
Storage: Keep tightly closed in a cool, dry place away from sunlight and heat. For long-term storage, refrigeration is acceptable when condensation is avoided.
INCI Name: Hydrolyzed Hyaluronic Acid
- Room (25-40C)
- 24 Months from manufacturing or testing date.
- 0.10% - 0.50%
- 0.10%
- Add into water phase. Avoid temperature above 60C.
- Avoid heat above 60C
- 3.00 - 9.00
- Soluble in Water
- Cream, Lotion, Serum
- -
| Test Name | Specification |
|---|---|
| Appearance | White or almost white powder or granule |
| Glucuronic Acid | Min 46.0% |
| Sodium Hyaluronate | Min 95.0% |
| Molecular Weight | 2000Da-3000Da |
| Intrinsic viscosity | 0.14-0.19dL/g |
| Kinematic viscosity | Reported on COA |
| pH(0.5% aq.sol.,25℃) | 5.0 - 8.5 |
| Protein | Max 0.1% |
| Absorbance(0.5% aq.sol.,25℃) | A280nm: Max 0.25 |
| Transmittance(0.5% aq.sol.,25℃) | T650nm: Min 99.0% |
| Loss on drying | Max 10.0% |
| Heavy Metal(as Pb) | Max 20ppm |
| Total plate count | Max 100 CFU/g |
| Yeasts & molds | Max 50 CFU/g |
| Staphylococcus aureus | Negative/g |
| Pseudomonas aeruginosa | Negative/g |
“Exact 2-kDa hyaluronic acid evidence: topical HA2k reduced facial spots and sagging after 4 weeks; in vitro data suggested autophagy and keratinocyte-turnover mechanisms.”
“Closest topical HA family evidence: 0.1% HA creams of different molecular weights improved skin hydration and elasticity; lower-MW groups improved wrinkle roughness versus placebo.”
“Closest topical HA serum evidence: a hyaluronic-acid facial serum improved hydration, plumpness, fine lines/wrinkles, and overall photoaged facial appearance in a clinical study.”
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